post-stroke depression
Conditions
Interventions
Drug group:fluoxetine hydrochloride capsules
Acupuncture and Drug Group:Tongdutiaoshen acupuncture combined with fluoxetine hydrochloride capsules
Sponsors
The second affiliated Hospital of Anhui University of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Meets both the above diagnostic criteria for stroke and depression; (2) Patients with mild to moderate neurological deficits, i.e. NIHSS = 14 points; (3) Stable vital signs, aged 40-75 years old; (4) Hamilton Depression Rating Scale (HAMD) score = 8 points; (5) No history of mental illness before stroke; (6) With the consent of the patient and their family members, an informed consent form shall be signed. Patients who meet the above six criteria at the same time can be included in this study.
Exclusion criteria
Exclusion criteria: (1) Severe loss of function, aphasia, memory decline, hearing comprehension, and cognitive impairment; (2) Patients with combined brain herniation, severe physical diseases such as heart, liver, lung, kidney, and hematopoietic system that cannot cooperate with the examination; (3) Individuals with a history of mental illness such as depression and anxiety or suicidal tendencies prior to stroke; (4) Individuals who regularly take various sedatives, psychotropic drugs, or have a history of alcohol dependence; (5) Excluding obvious cognitive impairment, illiteracy<17 points, and elementary school education using the Mini Mental State Examination (MMSE)<20 points, junior high school or above education<24 points. Anyone who conforms to any of the above shall be excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton depression scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Self-rating depression scale;activity of daily living;National Institute of Health stroke scale; | — |
Countries
China
Contacts
Public ContactPeiyang Sun
The second affiliated Hospital of Anhui University of traditional Chinese Medicine
Outcome results
None listed