rectal cancer
Conditions
Interventions
the total lesion resection group:NA
the non-full-layer resection group:NA
surgical operation group:NA
Sponsors
The First Medical Center of Chinese PLA General Hospita
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for total lesion resection:(1) Preoperative biopsy pathology indicated that HIN was cancerous or cancerous; Lesion size =2cm. (2) Complete clinical stage diagnosis was performed before surgery, including chest CT plain scan, abdominal pelvic CT plain scan + enhancement, superficial lymph node ultrasound, PET-CT, rectal MRI, endoscopic ultrasound and magnification endoscopy; (3) The clinical stage of colorectal cancer was cTisN0M0, cT1aN0M0 or cT1bN0M0. (4) Age: 18-80 years old; (5) Endoscopic therapy and laparoscopic surgery can be tolerated in general; (6) Patients and family members can understand the research protocol and voluntarily participate in the study, and sign informed consent. The inclusion criteria of the non-full-layer resection group were as follows: (1) Preoperative biopsy pathology indicated HIN with or without cancer; The size of the lesion is not limited. (2) Complete clinical stage diagnosis was performed before surgery, including chest CT plain scan, abdominal pelvic CT plain scan + enhancement, superficial lymph node ultrasound, rectal MRI, PET-CT, endoscopic ultrasound and magnification endoscopy; (3) The clinical stage was cTisN0M0 early intestinal cancer or intestinal HIN; (4) Age :18-80 years old; (5) The general condition can tolerate endoscopic therapy and laparoscopic lymph node resection; (6) Patients and family members can understand the research proposal, voluntarily participate in the study, and sign informed consent. The inclusion criteria of surgical operation group were as follows: (1) Preoperative biopsy pathology indicated HIN cancer or cancer or endoscopic unresectable lesions; The size of the lesion is not limited. (2) Complete clinical stage diagnosis was performed before surgery, including chest CT plain scan, abdominal pelvis CT plain scan + enhancement, rectal MRI, superficial lymph node ultrasound, PET-CT, endoscopic ultrasound and magnification endoscopy; (3) The clinical stage of colorectal cancer was cTisN0M0, cT1aN0M0 or cT1bN0M0; (4) Age :18-80 years old; (5) Laparoscopic and open radical surgery can be tolerated in general; (6) Patients and family members can understand the research protocol and voluntarily participate in the study, and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Previous history of gastrointestinal surgery; (2) Have a history of malignant tumors or other malignant tumors; (3) Combined with gastrointestinal bleeding and other emergencies; (4) Special groups: children, pregnant or lactating women, patients with mental illness; (5) Situations in which the researcher considers it inappropriate to be included; (6)Lymph node sampling or report did not conform to the criteria of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence free survival ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease Free Survival;Overall Survival;Curative resection rate; | — |
Countries
China
Contacts
Public ContactLinghu Enqiang
The First Medical Center of Chinese PLA General Hospita
Outcome results
None listed