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NAD+alleviates iron death induced by oxidative stress in fibrotic cataract

NAD+alleviates iron death induced by oxidative stress in fibrotic cataract

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400079680
Enrollment
Unknown
Registered
2024-01-09
Start date
2022-12-01
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cataract

Interventions

Test group:cataract
control group:none

Sponsors

Aier Eye Hospital of Wuhan University/Wuhan Aier Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: From 2022 to 2023, 20 patients with anterior subcapsular cataract diagnosed in our hospital for phacoemulsification were collected, and 20 normal lenses were taken from donor eyeballs of cornea transplantation matched with sex and age

Exclusion criteria

Exclusion criteria: Other types of cataract

Design outcomes

Primary

MeasureTime frame
GPX4 content;Fe2+ measurement;—

Secondary

MeasureTime frame
SLC7A1 content;LPO content;GSH GSSG content;ROS content;CCK8 measurement;—

Countries

China

Contacts

Public ContactBao Xianyi

Wuhan University Affiliated Aier Ophthalmology Hospital/Wuhan Aier Ophthalmology Hospital

baoxy08@sina.com+86 135 5466 6059

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026