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Study on the influencing factors of drug treatment of functional dyspepsia

Study on the influencing factors of drug treatment of functional dyspepsia

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400079677
Enrollment
Unknown
Registered
2024-01-09
Start date
2024-02-01
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional dyspepsia

Interventions

Patients with abnormal urine routine data were treated with omeprazole treatment group.:none
Patients with normal urine routine data were treated with omeprazole treatment group.:none
treatment group:Omeprazole combined with flupentixol and melitracen for 4 weeks.
control group:omeprazole treatment for 4 weeks.

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ( 1 ) In line with the Rome IV standard : upper abdominal pain, upper abdominal burning sensation, postprandial fullness, early satiety, one or more symptoms, and there is no evidence of organic disease that can explain the above symptoms ; the above symptoms existed for at least 6 months and met the above diagnostic criteria in the past 3 months. And completed gastroscopy, barium meal, blood routine, biochemistry, thyroid function, glycosylated hemoglobin, tumor marker screening, abdominal color Doppler ultrasound and other examinations ; ( 2 ) Age = 18 years old ; ( 3 ) The education level is primary school and above, can use WeChat and other Internet tools and have a certain reading comprehension ability.

Exclusion criteria

Exclusion criteria: ( 1 ) Gastroscopy and other examinations found systemic diseases, metabolic diseases and malignant tumors ; ( 2 ) Patients with irritable bowel syndrome with abdominal pain and changes in bowel habits as the main symptoms ; ( 3 ) Gastroesophageal reflux disease patients with acid reflux and heartburn as the main symptoms ; ( 4 ) Have a history of abdominal surgery ; ( 5 ) pregnant and lactating women ; ( 6 ) The scale was used to measure patients with mental disorders such as anxiety and depression and severe physical diseases ; ( 7 ) Reluctant to participate in the researchers.

Design outcomes

Primary

MeasureTime frame
Dyspepsia Symptom Severity Scale ( DSS );Niping Dyspepsia Index ( SF-NDI );

Secondary

MeasureTime frame
Patient Health Questionnaire Depression Symptom Cluster Scale ( PHQ-9 );Patient Health Questionnaire Somatization Symptom Cluster Scale ( PHQ-8 );Perceived Stress Scale ( PSS-4 );Urinary inflammatory index;

Countries

China

Contacts

Public ContactHe Guobin

Affiliated Hospital of North Sichuan Medical College

heguob@163.com+86 136 8822 3052

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026