zoster associated pain
Conditions
Interventions
test group:TFESI using bupivacaine liposomes
control group:TFESI using traditional bupivacaine hydrochloride
Sponsors
Nanjing First Hospital, Nanjing Medical University
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Patients with thoracic herpes zoster, the course of disease is less than 30 days; (2) Patients with pain VAS score still >=4 after outpatient treatment with first-line drugs treatment (pregabalin 150mg bid) or cannot be tolerated to drug treatment; (3) over the age of 50; (4) The patient was willing to receive transforaminal epidural injection; (5) Agree to participate in this study.
Exclusion criteria
Exclusion criteria: (1) There are contraindications of minimally invasive interventional therapy such as infection and coagulation function; (2) local anesthetics, fat emulsion allergy; (3) Patients with severe scoliosis and other spinal diseases who cannot complete puncture with ultrasound guidance alone; (4) Central nervous system disease; (5) Severe immunosuppressive diseases such as leukemia and lymphoma; (6) have received intrathecal drug injection treatment within 3 months; (7) Women during pregnancy; (8) Unable to complete the questionnaire and follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| NPSI;SIS;Oral analgesic dose;PHN incidence;SF-36 questionaire; | — |
Countries
China
Contacts
Public ContactXu Chenjie
Nanjing First Hospital, Nanjing Medical University
Outcome results
None listed