None
Conditions
Interventions
Propofol Group:The children were sedated with propofol
Remazolam Group:The children were sedated with remazolam
Sponsors
Peking University First Hospital Ningxia Women's and Children's Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital)
Eligibility
Sex/Gender
All
Age
1 Months to 1 Years
Inclusion criteria
Inclusion criteria: (1) Age between 1 month to 12 months; (2) Patients undergo elective surgery; (3) American Society of Anesthesiologists (ASA) Physical Status Classification I-III.
Exclusion criteria
Exclusion criteria: Those who meet one of the following criteria shall not be considered as selected cases: (1) Children or their legal guardians refuse to participate in this study; (2) Patients undergo cardiac or neurological surgery; (3) Patients with neurodevelopmental disorders or other neurological disorders. (4) Unable to complete delirium assessment due to visual or hearing impairment; (5) Deep sedation (Richmond Agitation Sedation Score -4 or -5) or in coma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparing the differences in brain network functional connectivity between the two groups of children; | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of differences in brain network functional connectivity between children with postoperative delirium and those without;Comparison of differences in brain network function connectivity among baseline, sedative state, after intubation, during surgery, and recovery state; | — |
Countries
China
Contacts
Public ContactKong Hao
Peking University First Hospital Ningxia Women's and Children's Hospital
Outcome results
None listed