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A comparative MRI study of changes in brain function in common symptoms of chronic obstructive pulmonary disease

A comparative MRI study of changes in brain function in common symptoms of chronic obstructive pulmonary disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079661
Enrollment
Unknown
Registered
2024-01-09
Start date
2024-01-11
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease

Interventions

Lung and spleen deficiency group:Nourish lungs and strengthen spleen granules
Lung and kidney qi deficiency group:Nourish the lungs and benefit the kidney granules

Sponsors

The First Affiliated Hospital of Henan University of CM
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients with stable COPD who meet the above diagnostic criteria with pulmonary function grade 3; 2. Patients with TCM differentiation consistent with lung and spleen qi deficiency and lung and kidney qi deficiency; 3. Age= 40 years old, = 75 years old; 4. Voluntarily receive treatment and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Have a clear history of head trauma and cerebrovascular disease: 2. Combined with serious uncontrollable diabetes, cardiovascular disease, liver and kidney failure and other serious systemic diseases: 3. Combined with obstructive sleep apnea syndrome: 4. Combined with Alzheimer's disease, psychiatric disease, hysteria and other diseases that may affect cognition 5. Install pacemakers, there are metals in the body, such as prosthetics, artificial valves, fixed steel plates, screws, etc.

Design outcomes

Primary

MeasureTime frame
N-acetylaspartic acid;choline;creatine;

Secondary

MeasureTime frame
Lung function;mMRC;CAT;Clinical symptoms and signs;mESQ-COPD;

Countries

China

Contacts

Public ContactLi Ning

The First Affiliated Hospital of He'nan University of Traditional Chinese Medicine

13526856957@163.com+86 135 2685 6957

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026