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Study on the efficacy, safety and mechanism of Bacillus coagulans in postoperative intestinal function recovery

Study on the efficacy, safety and mechanism of Bacillus coagulans in postoperative intestinal function recovery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079659
Enrollment
Unknown
Registered
2024-01-09
Start date
2024-01-23
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intestinal retardation after laparoscopy

Interventions

Control group:Routine treatment, no intervention, only records of relevant data.
Conventional dose group:Refer to the dosage instructions
Live Bacillus coagulans tablets were taken 1 hour after preoperative enema, 6 tablets were taken within 2 hours, 3 tablets were taken 8 hours after surgery, and 3 tablets were taken once every 8 hours
High dose group:Live Bacillus coagulans tablets were taken 1 hour after preoperative enema, 6 tablets were taken within 2 hours, 6 tablets were taken 8 hours after surgery, and 6 tablets were taken on

Sponsors

Shanxi Bethune Hospital,Shanxi Academy of Medical Sciences,Tongji Shanxi Hospital,Third Hospital of Shanxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: a. Age 18-65 years old; b. Have undergone laparoscopic surgery; c. The operation time is 1-4 hours; d. Willing to sign informed consent.

Exclusion criteria

Exclusion criteria: a. suffering from cognitive impairment, Alzheimer's disease, depression, etc.; b. Have a history of abdominal and intestinal surgery or are allergic to probiotics; c.. Intraoperative blood loss of more than 400mL; d.. Poor medication compliance, resulting in invalid results; e. within 3 months after participating in or completing another clinical trial.

Design outcomes

Primary

MeasureTime frame
First postoperative exhaust time;

Secondary

MeasureTime frame
Time of first postoperative defecation;Postoperative bowel sound recovery time;Length of stay;Incidence of postoperative complications;adverse event;

Countries

China

Contacts

Public ContactXu Juan

Shanxi Bethune Hospital,Shanxi Academy of Medical Sciences,Tongji Shanxi Hospital,Third Hospital of Shanxi Medical University

xujuanxp@163.com+86 159 3562 9607

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026