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Study on the effect and mechanism of transcranial alternating current stimulation in Gamma band of cerebellum to improve lower limb walking function

Study on the effect and mechanism of transcranial alternating current stimulation in Gamma band of cerebellum to improve lower limb walking function

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079657
Enrollment
Unknown
Registered
2024-01-09
Start date
2024-01-22
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

1:physical therapy +50 Hz cerebellar tACS
2:physical therapy + cerebellar tACS pseudostimulation

Sponsors

Yueyang Hospital of Integrated Chinese and Western Medicine affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Those who meet the diagnostic criteria (including cerebral infarction and cerebral hemorrhage); 2. Age =25 years old and =80 years old, duration of disease =1 year, gender unlimited; 3. Primary school education or above; 4. People who have independent or assisted walking ability but still have walking dysfunction (including but not limited to asymmetric walking pattern of bilateral lower limbs, slow walking speed, weak balance, etc.); 5.Holden walking function grade =2 6. Patients with Brunnstrom stroke recovery grade of lower extremity =3 7. The subject and his legal guardian understand and agree to participate in the study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with cerebellar lesion; 2. Patients who refuse or cannot cooperate with the therapist for routine training and cannot tolerate behavioral assessment for half an hour to one hour; 3. Patients with nerve or musculoskeletal diseases that affect walking function and are not caused by stroke, such as fresh unhealed fractures, joint pain, and ASL; 4. Serious heart, liver and kidney diseases, skin diseases, infectious diseases or pregnancy of women; 5. Obvious pain, sleep disorder, mental disorder; 6. There are taboos for TMS examination.

Design outcomes

Primary

MeasureTime frame
10 m time walking test;

Secondary

MeasureTime frame
time up and go;Berg balance scale;Limits of Stability;Functional near-infrared spectroscopy;Motor evoked potential;Gait Real-time Analysis Interactive;

Countries

People's Republic of China

Contacts

Public ContactChunlei Shan

Shanghai Jiao Tong University School of Medicine Rehabilitation Institute

shanclhappy@163.com+86 138 1621 5058

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026