sepsis
Conditions
Interventions
Sponsors
Northern Jiangsu People's Hospital Jiangsu Province
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients diagnosed with sepsis according to Sepsis 3: (1) Infection or highly suspected infection; ? and SOFA score =2 points; (2) Patients diagnosed with sepsis associated liver injury according to the Save Sepsis Campaign: ? bilirubin > 34.2µmol/L and international standardization ratio (INR) > 1.5; ALT or AST is 10 times higher than the upper limit of normal; (3) Age =18 years old; (4) Informed consent to the process and purpose of this study, voluntarily participate in and sign the informed consent;
Exclusion criteria
Exclusion criteria: (1) Acute onset of chronic liver disease or chronic liver dysfunction; (2) drug-induced liver injury; (3) History of liver transplantation; (4) Sepsis was diagnosed more than 24 hours before enrollment; (5) History of blood transfusion;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum iron;ferritin;Transferrin saturation;Total iron binding capacity;Soluble transferrin receptor;ALT;AST; | — |
Secondary
| Measure | Time frame |
|---|---|
| 28-day case fatality rate;Length of stay in ICU; | — |
Countries
China
Contacts
Public ContactShao Jun
Northern Jiangsu People's Hospital, Jiangsu Province
Outcome results
None listed