Multimodal anesthesia and retroperitoneal laparoscopic adrenalectomy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) American Society of Anesthesiologist physical status Classification I-III; (2) Patients aged 18-65 who plan to undergo retroperitoneal laparoscopic adrenalectomy; (3) Agree to participate in the study; (4) Can understand the relevant evaluation content; (5)BMI 18.5-28 kg/m2 .
Exclusion criteria
Exclusion criteria: (1) With severe comorbidities, including but not limited to renal dysfunction (creatinine>442) µmol/L or renal replacement therapy, liver dysfunction (Child Pugh C grade), and other serious cardiovascular and pulmonary diseases; (2) Contraindication of nerve block, including but not limited to be coagulation disorder, infection at the injection site, allergic to anesthetic drug; (3) Chronic pain patients or long-term use of various analgesics; (4) Preoperative consideration for patients with pheochromocytoma; (5) Individuals with anatomical abnormalities who are unable to undergo nerve block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The area under the curve of the average VAS score within 24 hours after surgery.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure and heart rate at different time points during surgery;Opioid consumption during different postoperative time periods ;the time interval to the first bolus demand in PCIA pump;intraoperative opioid consumptions;the numbers of rescue analgesia besides PCIA pump;the numbers of required boluses in PCIA pump;VAS scores at different postoperative time points during rest and movement;Ramsay scores at different postoperative time points;dermatomal distribution of sensory loss (after block);quality of recovery scores (QoR-15) at 24 and 48 hours postoperative; | — |
Countries
China
Contacts
The First Affiliated Hospital of Gannan Medical College