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Clinical efficacy evaluation of general anesthesia combined with ultrasound-guided intertransverse process block in retroperitoneal laparoscopic adrenalectomy: a three arm, double-blind, non inferiority randomized controlled trial

Clinical efficacy evaluation of general anesthesia combined with ultrasound-guided intertransverse process block in retroperitoneal laparoscopic adrenalectomy: a three arm, double-blind, non inferiority randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079650
Enrollment
Unknown
Registered
2024-01-08
Start date
2024-01-08
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multimodal anesthesia and retroperitoneal laparoscopic adrenalectomy

Interventions

ITPB group:Intertransverse process block
PVB group:Paravertebral block

Sponsors

The First Affiliated Hospital of Gannan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) American Society of Anesthesiologist physical status Classification I-III; (2) Patients aged 18-65 who plan to undergo retroperitoneal laparoscopic adrenalectomy; (3) Agree to participate in the study; (4) Can understand the relevant evaluation content; (5)BMI 18.5-28 kg/m2 .

Exclusion criteria

Exclusion criteria: (1) With severe comorbidities, including but not limited to renal dysfunction (creatinine>442) µmol/L or renal replacement therapy, liver dysfunction (Child Pugh C grade), and other serious cardiovascular and pulmonary diseases; (2) Contraindication of nerve block, including but not limited to be coagulation disorder, infection at the injection site, allergic to anesthetic drug; (3) Chronic pain patients or long-term use of various analgesics; (4) Preoperative consideration for patients with pheochromocytoma; (5) Individuals with anatomical abnormalities who are unable to undergo nerve block.

Design outcomes

Primary

MeasureTime frame
The area under the curve of the average VAS score within 24 hours after surgery.;

Secondary

MeasureTime frame
Blood pressure and heart rate at different time points during surgery;Opioid consumption during different postoperative time periods ;the time interval to the first bolus demand in PCIA pump;intraoperative opioid consumptions;the numbers of rescue analgesia besides PCIA pump;the numbers of required boluses in PCIA pump;VAS scores at different postoperative time points during rest and movement;Ramsay scores at different postoperative time points;dermatomal distribution of sensory loss (after block);quality of recovery scores (QoR-15) at 24 and 48 hours postoperative;

Countries

China

Contacts

Public ContactLifang Zhan

The First Affiliated Hospital of Gannan Medical College

zhanlifangzouping@163.com+86 1587971530

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026