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Study on the effectiveness of LSP intervention in children with autism spectrum disorders based on brain functional network analysis

Study on the effectiveness of LSP intervention in children with autism spectrum disorders based on brain functional network analysis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079637
Enrollment
Unknown
Registered
2024-01-08
Start date
2024-02-01
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism Spectrum Disorder

Interventions

Sponsors

Shanghai Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 6 Years

Inclusion criteria

Inclusion criteria: ASD children: ? Children diagnosed with ASD according to DSM-5; ? Age 3~6 years old, male or female; ? Gesell: DQ=55 or WPPSI/WISC-R: IQ=50; ? Residence in Shanghai during the intervention period; ? Parents of the children sign an informed consent and are willing to cooperate with the intervention training and comply with the requirements of the programme. Typical development children: ? Age 3~6 years old, male or female; ? Gesell: DQ=55 or WPPSI/WISC-R: IQ=50; ? Children's parents sign an informed consent form and arewilling to co-operate and comply with the relevant requirements.

Exclusion criteria

Exclusion criteria: ASD children: ? Children have features of ASD but with neurometabolic epilepsy or epilepsy as the etiology; ? Cerebral developmental disorders excluded by cranial CT and hearing abnormalities excluded by audiological examination; ? Chidren have brain function abnormalities due to hereditary diseases; ? Children refuse to participate in the study or are unable to be followed up for the specified period of the study. Typical development children: ? Children refuse to participate in the study or are unable to be followed up for the specified period of the study.

Design outcomes

Primary

MeasureTime frame
Resting functional connectivity;Autism diagnostic observation schedule(ADOS);

Secondary

MeasureTime frame
Childhood autism rating scale(CARS);Strengths and difficulties questionnaire(SDQ);

Countries

China

Contacts

Public ContactMa Chenhuan

Shanghai Children's Hospital

machenhuan@shchildren.com.cn+86 134 5632 2250

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026