Autism Spectrum Disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ASD children: ? Children diagnosed with ASD according to DSM-5; ? Age 3~6 years old, male or female; ? Gesell: DQ=55 or WPPSI/WISC-R: IQ=50; ? Residence in Shanghai during the intervention period; ? Parents of the children sign an informed consent and are willing to cooperate with the intervention training and comply with the requirements of the programme. Typical development children: ? Age 3~6 years old, male or female; ? Gesell: DQ=55 or WPPSI/WISC-R: IQ=50; ? Children's parents sign an informed consent form and arewilling to co-operate and comply with the relevant requirements.
Exclusion criteria
Exclusion criteria: ASD children: ? Children have features of ASD but with neurometabolic epilepsy or epilepsy as the etiology; ? Cerebral developmental disorders excluded by cranial CT and hearing abnormalities excluded by audiological examination; ? Chidren have brain function abnormalities due to hereditary diseases; ? Children refuse to participate in the study or are unable to be followed up for the specified period of the study. Typical development children: ? Children refuse to participate in the study or are unable to be followed up for the specified period of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting functional connectivity;Autism diagnostic observation schedule(ADOS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Childhood autism rating scale(CARS);Strengths and difficulties questionnaire(SDQ); | — |
Countries
China
Contacts
Shanghai Children's Hospital