Knee joint disease
Conditions
Interventions
group I:the parasacral ischial plane was injected with 133mg liposomal bupivacaine
group ?:the parasacral ischial plane was injected with 266mg liposomal bupivacaine
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Requires unilateral total knee arthroplasty; 2.Age 18-80 years; 3.ASA I-II grade; 4.BMI 18-30 kg/m2; 5.Voluntary and signed informed consent form; 6.Ability to walk independently for at least 20 meters; 7.Normal sensory function in the distribution area of the sciatic nerve.
Exclusion criteria
Exclusion criteria: 1.Patients with chronic pain; 2.Preoperative opioid therapy; 3.Allergic to the study drug; 4.Unable to use or understand patient-controlled analgesia (PCA) device; 5.Infection at the site of nerve block puncture; 6.Ultrasound could not identify the anatomical structure or identify the body surface location; 7.Nerve disorders; 8.Coagulation dysfunction; 9.Those who refuse to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score;Blocking onset time;Duration of sensory block;Duration of motor block;Consumption of opioid medications;Rescue analgesia time and frequency;Satisfaction with pain management; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of block procedure;Perioperative vital signs;Adverse reactions;Sedation score;Duration of hospitalization; | — |
Countries
China
Contacts
Public ContactZheng Ting
Department of Anesthesiology, Fujian Provincial Hospital
Outcome results
None listed