double-lumen bronchial intubation
Conditions
Interventions
Group C:Nebulized inhalation of saline 6 ml before induction of anesthesia
Group R:Nebulized inhalation of 0.5% ropivacaine 6 ml before induction of anesthesia
Group DR:Nebulized inhalation of 0.5% ropivacaine 6 ml plus 10 mg dexamethasone before induction of anesthesia
Sponsors
The First Affiliated Hospital of Gannan Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. ASA class I to III; 2. age 18 to 65 years; 3. body mass index 18 to 27.9 kg/m2; 4. thoracic surgery under elective general anesthesia with double-lumen bronchial intubation.
Exclusion criteria
Exclusion criteria: 1. anticipated difficulty in intubation; 2. recent history of cold, sore throat, hoarseness or pharyngolaryngitis; 3. indwelling gastric tube; 4. history of severe cardiovascular and cerebral vascular diseases; 5. severe abnormalities of liver and renal function; 6. allergy to the drugs used in the study; 7. severe diabetes mellitus, infections, and other diseases inappropriate for the use of hormones; 8. verbal communication barriers or other reasons for not being able to cooperate; 9. refusal to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence, pain visual analog score and severity rating of sore throat at rest;Incidence, pain visual analog score and severity rating of sore throat at swallowing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and severity rating of hoarseness;MAP;HR;Degree of extubation choking ;Degree of agitation during awakening;Postoperative incidence of nausea and vomiting, choking on drinking water, and reflux aspiration; | — |
Countries
China
Contacts
Public ContactJunming Ye
The First Affiliated Hospital of Gannan Medical University
Outcome results
None listed