Menopausal Syndrome
Conditions
Interventions
Test group:Taking Red Ginseng Beverage
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Menopausal women aged 45-60 years old who have undergone perimenopause and a period of time after perimenopause; 2. FSH (Follicle stimulating hormone) = 30 mIU/mL; 3. Individuals with a KI (kupperman Index) score higher than 25 and at least two of the following symptoms (insomnia, irritability, depression, fatigue) in the KI questionnaire are abnormal; 4. Sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Women with a body mass index (BMI) exceeding 30kg/m2; 2. Women who have taken female hormone or similar hormone preparations within three months; 3. People with endometrial hyperplasia, uterine cancer, endometrial cancer, breast cancer or breast diseases, and sex hormone related diseases; 4. Women with a history of cancer or other illnesses; 5. Patients undergoing hysterectomy; 6. Women who have experienced severe migraines, thromboembolism, cerebrovascular disease, myocardial infarction within the past year, and have been diagnosed with angina or have undergone coronary artery surgery; 7. Those who take medication related to hyperlipidemia or cardiovascular disease within three months; 8. Women who suffer from severe mental illnesses such as depression and anxiety, or are taking psychiatric and neurological related medications such as antidepressants and sleeping pills; 9. Those who take or inject treatment drugs due to abnormal uterine bleeding and related diseases after menopause; 10. Hypertensive patients with blood pressure higher than 160/100mmHg; 11. Diabetes patients with uncontrolled blood sugar (fasting blood sugar above 180mg/dL or drug use resumed due to diabetes within 3 months); 12. TSH at 0.1µU/mL below or 10µU/mL above Thyroid disease patients; 13. Abusers of drugs or alcohol; 14. When ALT or AST exceeds three times the normal upper limit value of the research institution; 15. When the serum Creatinine exceeds twice the normal upper limit value of the research institution; 16. Those who have used thyroid hormone preparations, Clonidine, anticoagulants, or antithrombotic agents within three months; 17. Those who take female menopause related medical products or health functional foods (vitamins and antioxidant products, fatigue related products, blood lipid and cardiovascular health related products, etc.) within one month; 18. Those who have taken human red ginseng related products within three months; 19. People who are taking osteoporosis treatment agents such as bisphosphonate preparations; 20. Vegetarians; 21. Patients with endometrial thickness>7mm; 22. The research leader believes that it is not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NO;endothelial Nitric Oxide Synthase;Endothelin-1;Kupperman index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Four items of blood lipid;Malondialdehyde;Superoxide dismutase;Glutathione peroxidase;Cortisol;Phosphate creatine kinase;Blood lactate;Beck depression inventory;Athens Insomnia Scale; | — |
Countries
China
Contacts
Public ContactLi Yanling
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed