Kawasaki Disease
Conditions
Interventions
intervention group:IVIG+solu-medrol 2mg/kg
control group:solu-medrol 2mg/kg
Sponsors
Shenzhen Children's Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: (1) Patients who meet the diagnostic criteria of Kawasaki disease in China in 2022 and do not respond to treatment with two doses of IVIG (2) Initial IVIG treatment within 10 days of the onset of the disease (3) Hospitalized in the cardiology Department of Shenzhen Children's Hospital with informed consent of the child's family members.
Exclusion criteria
Exclusion criteria: 1) The first IVIG treatment was given 10 days after the onset of the disease. (2) Patients who have received IVIG or hormone therapy in other hospitals. (3) Patients with combined shock or MAS requiring early application of hormone therapy. (4) There are contraindications for the use of experimental drugs such as hormones and IVIG. (5) If the fever ended after the second dose of IVIG, the case was not considered as a study object, but the relevant parameters of the case were recorded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coronary artery diameter; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heating time;Hospital stay;Hospitalization expenses; | — |
Countries
China
Contacts
Public ContactBoning Li
Shenzhen Children's Hospital
Outcome results
None listed