Necrotizing enterocolitis in preterm infants
Conditions
Interventions
probiotic group:Taking probiotics
Sponsors
Quanzhou Maternal and Child Health Hospital-Children's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Gestational age at birth <32 weeks and birth weight <1500 g, admission to hospital within 24 hours of birth, complete perinatal documentation
Exclusion criteria
Exclusion criteria: Severe infectious diseases, chromosomal abnormalities, congenital malformations of the gastrointestinal tract, severe malformations of other organs, and comorbid inherited metabolic disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Faecal metabolites;Serum cytokinesTNF-a;Tube feeding time;Serum cytokinesTLR-4;Serum cytokines IL-1ß;Serum cytokines NF-?B; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age at return to birth weight ;Time to central cannulation;Weight gain (g/day);Length of hospitalisation;hospital fees;Incidence of late-onset septicaemia;Incidence of feeding intolerance;Incidence of necrotising small bowel colitis; | — |
Countries
CHINA
Contacts
Public ContactWang Ruiquan
Quanzhou Maternal and Child Health Hospital-Children's Hospital, No.700 Fengze Street, Quanzhou, Fujian, China
Outcome results
None listed