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A single center registration study using echocardiography to evaluate left atrial/left atrial appendage anatomical mechanical function for prediction of the risk of thromboembolism in non-valvular atrial fibrillation

A single center registration study using echocardiography to evaluate left atrial/left atrial appendage anatomical mechanical function for prediction of the risk of thromboembolism in non-valvular atrial fibrillation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400079545
Enrollment
Unknown
Registered
2024-01-05
Start date
2024-01-05
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Interventions

one:echocardiography

Sponsors

Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age greater than 18 years old 2. Patients with paroxysmal or non-paroxysmal non valvular atrial fibrillation 3. Participants sign an informed consent form, are willing to participate in this study, and cooperate with observation and follow-up

Exclusion criteria

Exclusion criteria: 1. Valvular atrial fibrillation (including mitral stenosis with a valve area less than 1.5CM2 or with mechanical valve) 2. Patients with an expected survival time of less than 1 year 3. Individuals with esophageal diseases who cannot tolerate TEE examination or contraindications to TEE examination 4. Patients planning to undergo left atrial appendage occlusion 5. The subjects are unwilling to sign or withdraw their informed consent form, and are unwilling to participate in this study and cooperate with observation and follow-up

Design outcomes

Primary

MeasureTime frame
Establish a scoring system for predicting the risk of atrial fibrillation thromboembolism (Stroke/TIA/ST) using left atrial/left atrial appendage anatomical mechanical function indicators (SESE-MEVVST) evaluated by echocardiography, and compare its value in predicting the risk of atrial fibrillation thromboembolism with the previous CHA2DS2-VASc scoring system. Evaluate whether its value in predicting the risk of atrial fibrillation thromboembolism is better than the CHA2DS2-VASc scoring system;

Secondary

MeasureTime frame
Evaluation of the status and interrelationships of left atrial/left atrial appendage anatomical and mechanical functional indicators in patients with different CHA2DS2 VASc scores;Clarify the strength (RR value) and correlation of different left atrial/left atrial appendage anatomical and mechanical functional indicators in predicting the risk of atrial fibrillation thromboembolism, and screen out the main indicators with predictive value for atrial fibrillation thromboembolism risk;Compare the difference in the incidence of thromboembolic events between patients with normal and damaged left atrial/left atrial appendage anatomical mechanical function in low-risk (male = 1 point, female = 2 points) and high-risk (male = 2 points, female = 3 points) CHA2DS2-VASc scores, and evaluate whether the value of left atrial/left atrial appendage anatomical mechanical function indicators in predicting the risk of thromboembolic events in AF is better than CHA2DS2-VASc?;To compare the difference in the incidence of thromboembolic events between patients with normal and damaged left atrial/left atrial appendage anatomical mechanical function in catheter ablation, and further evaluate whether the value of left atrial/left atrial appendage anatomical mechanical function indicators in predicting thromboembolic risk in atrial fibrillation patients is better than the CHA2DS2-VASc score;

Countries

China

Contacts

Public ContactJiang Li Sheng

Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine

jiangdoctor@hotmail.com+86 180 1732 9198

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026