Atrial Fibrillation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age greater than 18 years old 2. Patients with paroxysmal or non-paroxysmal non valvular atrial fibrillation 3. Participants sign an informed consent form, are willing to participate in this study, and cooperate with observation and follow-up
Exclusion criteria
Exclusion criteria: 1. Valvular atrial fibrillation (including mitral stenosis with a valve area less than 1.5CM2 or with mechanical valve) 2. Patients with an expected survival time of less than 1 year 3. Individuals with esophageal diseases who cannot tolerate TEE examination or contraindications to TEE examination 4. Patients planning to undergo left atrial appendage occlusion 5. The subjects are unwilling to sign or withdraw their informed consent form, and are unwilling to participate in this study and cooperate with observation and follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Establish a scoring system for predicting the risk of atrial fibrillation thromboembolism (Stroke/TIA/ST) using left atrial/left atrial appendage anatomical mechanical function indicators (SESE-MEVVST) evaluated by echocardiography, and compare its value in predicting the risk of atrial fibrillation thromboembolism with the previous CHA2DS2-VASc scoring system. Evaluate whether its value in predicting the risk of atrial fibrillation thromboembolism is better than the CHA2DS2-VASc scoring system; | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of the status and interrelationships of left atrial/left atrial appendage anatomical and mechanical functional indicators in patients with different CHA2DS2 VASc scores;Clarify the strength (RR value) and correlation of different left atrial/left atrial appendage anatomical and mechanical functional indicators in predicting the risk of atrial fibrillation thromboembolism, and screen out the main indicators with predictive value for atrial fibrillation thromboembolism risk;Compare the difference in the incidence of thromboembolic events between patients with normal and damaged left atrial/left atrial appendage anatomical mechanical function in low-risk (male = 1 point, female = 2 points) and high-risk (male = 2 points, female = 3 points) CHA2DS2-VASc scores, and evaluate whether the value of left atrial/left atrial appendage anatomical mechanical function indicators in predicting the risk of thromboembolic events in AF is better than CHA2DS2-VASc?;To compare the difference in the incidence of thromboembolic events between patients with normal and damaged left atrial/left atrial appendage anatomical mechanical function in catheter ablation, and further evaluate whether the value of left atrial/left atrial appendage anatomical mechanical function indicators in predicting thromboembolic risk in atrial fibrillation patients is better than the CHA2DS2-VASc score; | — |
Countries
China
Contacts
Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine