Skip to content

A multicenter, randomized, double-blind, placebo, parallel-controlled clinical trial of celecoxib in combination with Golden Tenge capsules for the treatment of osteoarthritis of the knee

A multicenter, randomized, double-blind, placebo, parallel-controlled clinical trial of celecoxib in combination with Golden Tenge capsules for the treatment of osteoarthritis of the knee

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079541
Enrollment
Unknown
Registered
2024-01-05
Start date
2023-03-21
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

one:Jintiange and celecoxib
two:Jintiange Placebo and Celecoxib

Sponsors

The Second Affiliated Hospital Of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Patients who meet the clinical diagnostic criteria for osteoarthritis of the knee. (2) Age 40-70 years old with no restriction on gender. (3) Body mass index (BMI) = 35 kg/m2 (4) Subject's KOA staging is in remission, recovery. (5) VAS score = 7. (6) Patients who have not undergone KOA systemic treatment within 3 months and who can adhere to the treatment schedule and can cooperate with clinical observation and follow-up. (7) Subjects understood and signed the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Traumatic arthritis of the knee joint; acute joint injury, osteoarthritic tuberculosis of the knee, tumors, rheumatoid arthritis, rheumatoid arthritis. (2) Patients who have undergone knee replacement. (3) Patients with combined cardiovascular, cerebrovascular, hepatic, renal and hematopoietic system and other serious primary diseases, tumors and psychiatric patients, neuropathic arthralgia, gastric ulcers. (4) Patients who have used drugs known to cause damage to major organs within 4 weeks. (5) Patients who are allergic to the drug components associated with this test. (6) Pregnant and lactating women. (7) Those who have taken herbal tonics, proprietary Chinese medicines or other western medicines for the treatment of osteoarthritis of the knee within the last two weeks (8) Patients who are unable to cooperate or are participating in other drug trials.

Design outcomes

Primary

MeasureTime frame
WOMAC;

Countries

China

Contacts

Public ContactWang Wei

The Second Affiliated Hospital Of Xi'an Jiaotong University

dr.wangwei@xjtu.edu.cn+86 29 8767 8326

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026