lung diseases
Conditions
Interventions
Group E:Preoperative ultrasound-guided ESPB and a postoperative multimodal analgesic regimen including sufentanil PCIA, i.v. dexmedetomidine, ibuprofen and dezocine.
Group T:Preoperative ultrasound-guided TPVB and a postoperative multimodal analgesic regimen including sufentanil PCIA, i.v. dexmedetomidine, ibuprofen and dezocine.
Group C:and a postoperative multimodal analgesic regimen including sufentanil PCIA, i.v. dexmedetomidine, ibuprofen and dezocine.
Sponsors
Beijing Children's Hospital, National Center for Children's Health, Capital Medical University
Eligibility
Sex/Gender
All
Age
7 Years to 18 Years
Inclusion criteria
Inclusion criteria: Age: 7-18 years old; Scheduled for VATS under general anesthesia; ASA physical status of I-II.
Exclusion criteria
Exclusion criteria: Failure to sign informed consent; Had contraindications to TPVB (vertebral anomalies, scoliosis, coagulopathy, local infection at planned injection sites, or receiving anticoagulation medication); Severe cardiopulmonary dysfunction, hepatic or renal insufficiency; allergy to any medication used in the study; obesity; chronic pain characterized or opioid use for over 3 months preoperatively; unable to cooperate in the pain assessment; psychiatric disorders or taking psychiatric medications; did not have a guardian able to use the parent-controlled intravenous analgesia (PCIA) pump.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative 24 h sufentanil PCIA consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| Numeric rating scale (NRS) at different postoperative time points;Sufentanil PCIA consumption at different postoperative time points;Rescue analgesia;Postoperative recovery status;Postoperative complications;Length of hospital stay;Ropivacaine blood concentration; | — |
Countries
CHINA
Contacts
Public ContactJIANMIN ZHANG
Beijing Children's Hospital, National Center for Children's Health, Capital Medical University
Outcome results
None listed