Elective surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged > 18 years;; 2. BMI 18-30kg/?; 3. ASAI-III grade; 4. Normal cognitive ability and communication ability; 5. Agree to sign the informed consent
Exclusion criteria
Exclusion criteria: 1. History of severe drug dependence, alcoholism; 2. Comorbid psychiatric disorders, central and peripheral nervous system disorders; 3. preoperative concomitant anxiety or depression; history of severe cardiac, hepatic, and renal impairment; 4. history of multiple surgeries; 5. chronic pain or being treated with opioids; 6. hearing impairment; 7. allergy to anesthetics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale(VAS at rest,VAS on coughing); | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of awakening;Anxiety index;Cortical excitability index;Fatigue index;PCIA presses;Consumption of analgesic drugs;Emergency analgesic dosage;Number of episodes of nausea and vomiting;Dosage of antiemetic drugs;Cyclic indicators;Depth of anesthesia;Dosage of anesthetics;Sex;Age;Body mass index (BMI);ASA classification;Surgery time;Blood volume;Complicating disease;Post-operative stress; | — |
Countries
China
Contacts
The Fourth Hospital of Hebei Medical University