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A standardized study on the clinical efficacy and neural function repair mechanism of Jin San-acupuncture in the treatment of vascular mild cognitive impairment

A standardized study on the clinical efficacy and neural function repair mechanism of Jin San-acupuncture in the treatment of vascular mild cognitive impairment

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079520
Enrollment
Unknown
Registered
2024-01-05
Start date
2024-01-08
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vascular mild cognitive impairment

Interventions

Acupuncture group:Jin San-acupuncture therapy
false acupuncture group:false acupuncture

Sponsors

First Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for vascular mild cognitive impairment in the 2016 Chinese Guidelines for the Diagnosis of Vascular mild Cognitive Impairment; 2. Age 35-90 years old, male or female, education level of junior high school or above; 3. The degree of cognitive impairment is mild, that is, the Montreal Cognitive Scale (MoCA) score (Beijing edition) : the score is between 14-25 points, and those with less than 12 years of education should be between 13-24 points; 4. no obvious visual and hearing impairment; 5. The ability of daily living activities is basically normal, and the muscle strength is =3; 6. The onset time should be greater than 7 days; 7. no serious mental illness; 8. stable vital signs, and can cooperate with traditional Chinese and western rehabilitation treatment; 9. Informed consent, voluntary cooperation with the test; I or legal guardian agree and sign the informed consent; 10. Right-handed

Exclusion criteria

Exclusion criteria: Anyone who meets any of the following criteria shall be excluded (1) Medical history or family members confirmed that they had related diseases affecting cognitive function before the onset of the disease; (2) Patients with coagulation dysfunction and bleeding risk, patients who can not tolerate acupuncture treatment; Combined with severe heart, liver, lung and renal insufficiency; (3) Those who have received relevant oral medication or other treatment to improve cognitive function within the past one month;

Design outcomes

Primary

MeasureTime frame
Montreal cognitive assessment;Serum alpha-synuclein;

Secondary

MeasureTime frame
mini-mental state examination;Instrumental Activity of Daily Living;

Countries

China

Contacts

Public ContactShuxin Wang

First Affiliated Hospital of Guangzhou University of Chinese Medicine

widiot@126.com+86 136 6028 5076

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026