Gynecological operation
Conditions
Interventions
Group of general anesthesia combined with epidural block:General anesthesia combined with epidural block
Group of only general anesthesia:only general anesthesia
Sponsors
Guangzhou Women and Children's Medical Center
Eligibility
Sex/Gender
Female
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective gynecological laparoscopic surgery 2.ASA classification I-II. 3. The estimated operation time is more than 2h. 4. Agree to use patient-controlled analgesia (PCA) after operation.
Exclusion criteria
Exclusion criteria: 1. History of cognitive dysfunction 2. Severe neurological disease, acute myocardial infarction or stroke within the 3 months, 3. Any contraindications to epidural anesthesia 4. Patients with severe heart dysfunction, severe liver dysfunction (Child-Pugh grade C) or renal failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative 24-hour pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative cognitive function score;Postoperative delirium;Laboratory blood test;Intraoperative vital signs;Postoperative analgesic drug use;vasoactive drug dosage; | — |
Countries
China
Contacts
Public ContactShe ying Jun
Guangzhou Women and Children's Medical Center
Outcome results
None listed