diabetic kidney disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Type 2 diabetes patients; 2) Age range from 40 to 85 years old, regardless of gender; 3) Estimated glomerular filtration rate (eGFR)>15 ml/min/1.73 m2 (CKD-EPI formula); And or 24 hour urine protein quantity>0.5g or kidney disease symptoms in patients with diabetes and kidney disease; 4) Able to understand the procedures and methods of this clinical study, correctly express willingness, voluntarily participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Non T2DM patients; 2) T2DM patients with known malignant tumors, or lactic acidosis, or ketoacidosis, or severe infections, or critically ill patients (such as organ failure, heart failure, myocardial infarction, cerebral infarction, etc.); 3) Have a history of primary thyroid disease and thyroid autoimmune disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pyrosis associated proteins (GSDMD, caspase-1, IL-1) ß, IL-18);Urinary protein creatinine ratio;glomerular filtration rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| renal function;blood fat;Coagulation indicators;blood sugar;Blood routine; | — |
Countries
China
Contacts
Hebei Yiling Hospital of Hebei Medical University