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Clinical Study on Acupuncture Treatment of Post-stroke Dysphagia Based on "Differentiation of Meridians and Treatment"

Research on Key Technologies and Standardized Diagnosis and Treatment Plans for Acupuncture Treatment of Post-stroke Dysphagia Based on "Differentiation of Meridians and Treatment"

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079472
Enrollment
Unknown
Registered
2024-01-04
Start date
2024-01-05
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-stroke dysphagia

Interventions

Acupuncture group:acupuncture treatment (Baihui, Fengfu, Tiantu, Lianquan, Jinjin, Yuye, Renying, Wangu, Yifeng, Neiguan+ acupoints by distinguishing meridians)
Control Group I:acupuncture treatment (Fengfu, Bailao, Renying, Lianquan, Jialianquan)
Control Group II:Conventional rehabilitation: ? Sensory stimulation: Cold stimulation in the pharynx, use a frozen cotton swab to stimulate the pharynx and tongue base, instruct the patient to swallow
? Swallow empty, three times a day, for 20 minutes each time before breakfast, lunch, and dinner
? Tongue movement facilitation involves horizontal, backward, and lateral movements of the tongue, with resistance provided by a spoon or tongue depressor to create resistance movements, twice a day.
Repeatedly making "eight, eight, clap, clap" sounds
Blowing air can prevent lip stiffness and maintain the optimal physiological shape of the lips, preventing the outflow of oral fluids and food. Maintain lip position for 5-10 seconds, twice a day
? Cough training: Strive to cough and establish a defense reflex to eliminate tracheal foreign bodies.? Feeding training: Patients should sit, lie half or flat, raise their heads 30-40°, eat liquid or

Sponsors

The Second Affiliated Hospital of Anhui University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) the patients met the diagnostic criteria for stroke diagnosis and efficacy evaluation, diagnostic criteria for various cerebrovascular diseases, and the consensus of experts in the evaluation and treatment of swallowing disorders in China (2017 version); (2) the life signs were stable after regular treatment and the course of the disease was less than 3 months; (3) the patients had the clinical manifestations of dysphagia and cough after drinking water; (4) dyskinesia of soft palate, pharynx, tongue, the masseter or facial muscles, no atrophy of tongue muscle and tremor of tongue muscle; (5) physiological brainstem reflex: existence or hyperactivity of soft palate reflex, hyperactivity of mandibular reflex. The pathological brainstem reflex was positive; (6) Those who voluntarily participate in this clinical trial, and sign an informed consent form.

Exclusion criteria

Exclusion criteria: (1) cases of large-area cerebral infarction and severe cerebral hemorrhage; (2) cases of true bulbar paralysis; (3) cases of pseudobulbar paralysis over 90 days; (4) cases of disturbance of consciousness; (5) cases of cognitive dysfunction; (6) patients with severe multiple organ dysfunction syndrome, (7) patients who failed to complete the acupuncture treatment according to the experimental plan, (8) patients who had contraindications to MRI examination such as claustrophobia and metal implants; (9) severe asymmetry of cranial anatomy or definite lesions were found in MRI scan.

Design outcomes

Primary

MeasureTime frame
water swallow test and Blood oxygen saturation detection;Standard Swallowing Function Assessment Scale (SSA);Videofluorographic swallowing study score;Detection of monoamine neurotransmitter content [?- Aminobutyric acid (GABA), glutamic acid (GA), acetylcholine receptor (AChR), 5-hydroxytryptamine (5-HT), acetylcholine (ACh), norepinephrine (NE), dopamine (DA)];Evaluation of cortical medullary tract brain DTI;

Secondary

MeasureTime frame
Immune function and nutritional indicators (TLC, IgG, IgA, Hb, ALB, STP);Effective rate;incidence of adverse reactions;clinical symptoms and signs of patients;

Countries

China

Contacts

Public ContactHongliang Cheng

The Second Affiliated Hospital of Anhui University of Chinese Medicine

chl.75811@163.com+86 130 1309 2266

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026