Postoperative pulmonary complications
Conditions
Interventions
Control group:VT is 8~10ml/kg, suction ratio 1:2, PEEP and recruitment are not used
Lung-protective ventilation strategy group:VT is 6~8ml/kg, syction ratio 1:2, optimal PEEP: optimal compliance method, intermittent volume pulmonary resuscitation
Sponsors
The General Hospital of Western Theater Command
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years 2. Non-craniocerebral trauma patients to be put under general anesthesia 3. Expected duration of mechanical ventilation =2h 4. ASA classification I-III; 5. No history of severe allergy; 6. Signed informed consent to participate in this study voluntarily
Exclusion criteria
Exclusion criteria: 1. Presence of acute lung injury preoperatively 2. presence of acute respiratory distress syndrome or respiratory failure within the past 3 months 3. Presence of critical illness, including severe hepatic dysfunction (hepatic failure or Child-Pugh score B or C); 4. Presence of chronic renal failure (glomerular filtration rate grade 2); 6. those who, in the opinion of the investigator, are not suitable for participation in this clinical trial; and 7. patients who are critically ill prior to surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications in the first 7 days postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of pulmonary complications 7 days after surgery;Inflammatory factors;Number of days of hospital stay after surgery;Mortality at 30 days after surgery;Postoperative pain score; | — |
Countries
China
Contacts
Public ContactQin Li
The General Hospital of Western Theater Command
Outcome results
None listed