prostate cancer
Conditions
Interventions
Gold Standard:The gold standard for diagnosing prostate cancer is prostate system biopsy in this project.
Index test:Index test:p2PSA, %p2PSA, PHI
Sponsors
The Second Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
Male
Age
50 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Male. 2.At least 50 years old. 3.Serum PSA test was performed in the Second Affiliated Hospital of Kunming Medical University, the test results were 4-10ng/ml, and no catheterization, prostate massage, urethra or perineal trauma was performed before PSA test. Patients with urinary catheterization, prostate massage, or urethral or perineal trauma before PSA screening were admitted to the study group if serum PSA was 4-10ng/ml 3 months later. 4.The digital rectal examination was negative ( the digital rectal examination did not reach the hard or hard nodules of the prostate. 5.Ultrasound and MRI revealed no suspicious lesions. 6.The blood clotting function is normal. If the patient takes aspirin, clopidogrel and other anticoagulants for a long time, the drugs should be stopped for at least 1 week. 7.Volunteer to participate in this clinical trial, understand the study procedures and have signed the informed consent.
Exclusion criteria
Exclusion criteria: 1.Serum PSA10ng/ml. 2.After electroprostatectomy. 3.After radical surgery for prostate cancer. 4.The patient had obvious coagulation dysfunction. 5.Acute prostatitis or acute inflammation of the prostate piercing area. 6.Prostate biopsy is not possible for anal and rectal lesions(such as low tumor). 7.Lower limb dyskinesia can not match puncture position. 8.Other serious systemic diseases such as poorly controlled high blood pressure, severe diabetes, neurological or mental illness, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prostate-specific antigen isomer 2(PSA); | — |
Secondary
| Measure | Time frame |
|---|---|
| %pProstate-specific antigen isomer 2(%PSA);prostate health index(PHI);sensitivity;specificity; | — |
Countries
China
Contacts
Public ContactDaoqi Wang
The Second Affiliated Hospital of Kunming Medical University
Outcome results
None listed