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Clinical regression of intracranial atherosclerotic stenosis interventions assessed by high-resolution imaging histology of the vessel wall

Clinical regression of intracranial atherosclerotic stenosis interventions assessed by high-resolution imaging histology of the vessel wall

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400079463
Enrollment
Unknown
Registered
2024-01-03
Start date
2024-01-05
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerotic stenosis of intracranial arteries

Interventions

Restenosis group vs. Non-restenosis group:No intervention

Sponsors

Jining No.1 People's Hospital, Shandong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Angiography (DSA) showing =70% stenosis of intracranial arteries; (2) Transient ischemic attack (TIA) or stroke associated with symptomatic intracranial atherosclerotic stenosis; and (2) Having a transient ischemic attack (TIA) or stroke associated with symptomatic intracranial atherosclerotic stenosis; and (3) Recurrent transient ischemic attacks or strokes despite optimal drug therapy; and (4) Age between 18 and 80 years; and (5) More than 7 days or more have elapsed since the most recent stroke.

Exclusion criteria

Exclusion criteria: (1) Non-atherosclerotic stenosis; and (2) Other serious disease, such as heart or kidney failure; and (3) Experienced intracranial hemorrhage within the past 3 months; and (4) have contraindications to endovascular procedures, such as contrast allergy.

Design outcomes

Primary

MeasureTime frame
High Resolution Imaging Histology;

Secondary

MeasureTime frame
Vascular wall plaque distribution;Vessel wall plaque load;Vessel wall plaque signal intensity;Vessel wall plaque enhancement index;Vessel wall plaque enhancement type;Vessel remodeling type;

Countries

China

Contacts

Public ContactHuakun Liu

Jining No.1 People's Hospital, Shandong

woshiliuhuakun@163.com+86 150 2078 0736

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026