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Clinical study of ultrasound-guided cryoablation with full-core biopsy after microwave ablation to accelerate volume reduction in benign thyroid nodules

Clinical study of ultrasound-guided cryoablation with full-core biopsy after microwave ablation to accelerate volume reduction in benign thyroid nodules

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079451
Enrollment
Unknown
Registered
2024-01-03
Start date
2024-01-03
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign thyroid nodules

Interventions

The test group:The benign thyroid nodules are treated with microwave ablation plus frozen whole-core spinning.
The control group:The benign thyroid nodules are treated with microwave ablation

Sponsors

West China Hospital of Sichuang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Ultrasound suggestive of benign, fine-needle aspiration biopsy with cytopathologic findings of Bethesda class 2 or histologic biopsy pathology confirming a benign nodule; (2) Solid nodules (solid component >95%), symptomatic or growing, in need of treatment, who strongly refuse surgery and request ablation.; (3) Nodules diameter =2cm at maximum; (4) Patients with high-functioning thyroid adenomas with malignancy ruled out by puncture, unwilling to undergo surgery, unwilling to undergo iodine 131 treatment or long-term medication, and requesting ablation.

Exclusion criteria

Exclusion criteria: (1) Contralateral vocal cord dysfunction; (2) Severe coagulation disorders; (3) Vital organ insufficiency (VOI); (4) Those who cannot co-operate with the surgery.

Design outcomes

Primary

MeasureTime frame
Sample volume;Sample weight;Focal size;

Secondary

MeasureTime frame
Focal location;

Countries

China

Contacts

Public ContactLu Qiang

West China Hospital of Sichuang University

luqiang@scu.edu.cn+86 138 8217 5090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026