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A real-world study on the relationship between steady-state blood concentration of colistin sulfate and the efficacy and safety of treatment in patients with ICU

A real-world study on the relationship between steady-state blood concentration of colistin sulfate and the efficacy and safety of treatment in patients with ICU

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400079446
Enrollment
Unknown
Registered
2024-01-03
Start date
2024-01-03
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ICU infectious disease

Interventions

Valid group and invalid group:None

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) the age of the patient is = 18 years old. (2) ICU patients treated with colistin sulfate for injection. (3) informed consent signed by the patient or his legal representative

Exclusion criteria

Exclusion criteria: (1) pregnant and lactating women. (2) patients with less than 5 doses of colistin sulfate for injection. (3) patients who received other polymyxin treatment 7 days before inclusion. (4) those who are known to be allergic to colistin sulfate. (5) it has been included in other clinical studies, and intervention measures will affect the results of this study. (6) other situations in which the researchers consider it inappropriate to participate in this clinical trial.

Design outcomes

Primary

MeasureTime frame
Efficacy and safety of colistin sulfate in patients with ICU;

Secondary

MeasureTime frame
ICU mortality rate;28 day outcome indicators;The incidence of acute renal insufficiency;

Countries

China

Contacts

Public ContactZhongwei Zhang

West China Hospital, Sichuan University

716461751@qq.com+86 133 0820 3057

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026