Craniotomy in neurosurgery
Conditions
Interventions
Group R:Anesthesia with remazolam
Sponsors
West China Hospital Of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) ASA I-II; 2) Age 18-65; 3) Patients undergoing elective neurosurgery who need to undergo lumbocisterna puncture and catheterization before surgery;
Exclusion criteria
Exclusion criteria: 1) Preoperative consciousness disorder, intubation; 2) Clearly have high cranial pressure; 3) Allergic to benzodiazepines, propofol and other drugs; 4) Severe cardiopulmonary disease; 5) liver and kidney dysfunction; 6) Long-term use of sedatives and anticoagulants. 7) lumbar puncture site had trauma, infection and so on.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in intracranial pressure;Cerebral perfusion pressure level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Success rate of electrophysiological monitoring;Postoperative extubation time;Adverse event occurrence rate; | — |
Countries
China
Contacts
Public ContactYang Lei
West China Hospital of Sichuan University
Outcome results
None listed