carotid artery stenosis
Conditions
Interventions
test group:Lonicerae Japonicae Caulis granules (equivalent to 90g of original medicinal materials), take it orally, 1 bag / time, 2 times / day, half an hour after the meal
control group:Lonicerae Japonicae Flos granules (equivalent to 90g of original medicinal materials), take it orally, 1 bag / time, 2 times / day, half an hour after the meal
Sponsors
Dongzhimen Hospital, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Carotid artery stenosis was confirmed by color Doppler ultrasound(confirmed by copy of the ultrasound report within 12 months); 2. hsCRP=2mg/L; 3. Age from 40 to 70 years, gender unlimited; 4. Adherence to the medication for 2 weeks; 5. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with acute phase of cardiovascular or cerebrovascular disease; 2. Patients with history of cerebral hemorrhage; 3. Patients with active ulcer or bleeding tendency; Patients taking anticoagulants for a long time; 4. Patients with severe arrhythmia, atrial fibrillation, or heart failure; 5. Patients with severe hematopoietic system, endocrine system, respiratory system, infection, immunity and other primary diseases;Patients whose transaminase is more than 1.5 times above the upper limit of normal; Patients whose creatinine is above the upper limit of normal; 6. Patients using medicine like Traditional Chinese medicine which clearing away heat and toxic, antibiotics, corticosteroids, immunosuppressants, IL-1 ß monoclonal antibodies that affecting hsCRP; 7. Pregnant or lactating women, women with recent pregnancy plans; 8. Patients with allergic constitution; 9. Patients with any other life-threatening or serious disease; 10. Patients with psychosis or other disease that may impact evaluation; 11. Patients who have attended clinical trials in the last 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum hypersensitive C-reactive protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-1ß;IL-6;blood lipids;Fasting blood glucose;TCM Symptoms and Signs; | — |
Countries
China
Contacts
Public ContactWu Shengxian
Dongzhimen Hospital, Beijing University of Chinese Medicine
Outcome results
None listed