Skip to content

Comparison of remimazolam and propofol on postoperative sleep quality in breast cancer surgery:A randomized non-inferiority trial

Comparison of remimazolam and propofol on postoperative sleep quality in breast cancer surgery:A randomized non-inferiority trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079385
Enrollment
Unknown
Registered
2024-01-02
Start date
2024-01-08
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

Group P:Propofol 4.0mg/kg/h continuous pumping combined with 2% sevoflurane continuous inhalation
Group R:Remimazolam1.0mg/kg/h continuous pumping combined with 2% sevoflurane continuous inhalation

Sponsors

Sun Yat-sen University Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Women; Age 18-60 years old; ASA grading I to II; The patient was diagnosed as breast cancer before operation and planned to be operated.

Exclusion criteria

Exclusion criteria: Allergies to drugs in the study protocol; Having sleep disorders requires medication intervention; Taking psychotropic drugs; Preoperative radiotherapy and chemotherapy; Those with severe cardiovascular, liver, kidney, and blood system diseases; BMl>30kg/m2; Inflammatory breast cancer; Previous breast cancer surgery history.

Design outcomes

Primary

MeasureTime frame
subjective sleep quality on the night of surgery;

Secondary

MeasureTime frame
postoperative quality of recovery;Withdrawal time and awakening time;The incidence of intraoperative and postoperative adverse events;

Countries

China

Contacts

Public ContactLin Wenqian

Sun Yat-sen University Cancer Center

linwq@sysucc.org.cn+86 138 2514 9286

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026