Chronic heart failure (Qi-Yin deficiency syndrome)
Conditions
Interventions
experimental group:GDMTplus 5.2g Yiqi Fumai Lyophilized Injection in 5% GS or 0.9% NS injection 250ml,qd for 10days
control group:Guideline-directed medical therapy(GDMT) treatment
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. All the patients are in accordance with the diagnostic criteria of Qi-Yin deficiency syndrome of chronic heart failure; 2. Aged 18 to 90; 3. Cardiac function classification: New York Heart Association (NYHA) II to III; 4. The patient gives informed consent and signs the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with chronic heart failure who need medical treatment in the near future; 2. Patients complicated with acute coronary syndrome (within 30 days), cardiogenic shock, acute myocarditis, hypertension (systolic blood pressure >= 180mmhg and / or diastolic blood pressure >= 110mmhg), malignant arrhythmia, hypertrophic obstructive cardiomyopathy, severe valvular disease requiring surgical treatment and pulmonary embolism, etc; 3. Severe hepatic and renal insufficiency; 4. Severe anemia; 5. Psychopath; 6. Cancer patients; 7. Patients participating in drug clinical trials in recent months; 8. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Veterans Specific Activity Questionnaire (VSAQ); | — |
Secondary
| Measure | Time frame |
|---|---|
| New York Heart Association (NYHA) classification;Electrocardiogram(ECG);Ultrasonic Cardiogram(UCG);6 min walking distance test;BNP/ NT-proBNP;The Kansas city cardiomyopathy questionnaire (KCCQ);Syndrome rating Score;liver function(ALT,AST);renal function(CREA,BUN); | — |
Countries
China
Contacts
Public ContactShichao Lv
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed