The effect of low-dose Espex Ketamine on postoperative restlessness in patients undergoing holmium laser lithotripsy

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400079365

Enrollment

Unknown

Registered

2024-01-02

Start date

2024-01-10

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative agitation

Interventions

S-ketamine group:a bolus of 0.2 mg/kg of S-ketamine during the period of anesthesia induction

Control group:a bolus of 0.2 mg/kg of normal saline during the period of anesthesia induction

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Patients who choose to undergo holmium laser lithotripsy; (2) Age 18-65 years old; (3) ASA classification II-III; (4) Agree to accept this experiment and sign an informed consent form

Exclusion criteria

Exclusion criteria: (1) Take painkillers or sedatives 24 hours before surgery; (2) Have a history of serious cardiovascular disease; (3) History of neurological or psychiatric disorders; (4) Long term alcoholism.

Design outcomes

Primary

Measure	Time frame
Richmond Agitation-Sedation Scale;	—

Secondary

Measure	Time frame
Heart rate, blood pressure, blood oxygen saturation;The incidence of coughing;Nausea and vomiting incidence rate;IL-6;	—

Countries

China

Contacts

Public ContactLi Jianli

Hebei General Hospital

1350630178@qq.com+86 183 3018 2389

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026