Stomach cancer
Conditions
Interventions
Experimental group (paracetamol mannitol injection + TAPB nerve block group):Thirty minutes before induction of anesthesia, TAPB nerve block was performed under the guidance of ultrasound and 1 g of p
Control Group (Sufentanil and TAPB nerve block group):Thirty minutes before anesthesia induction, TAPB nerve block was performed under the guidance of ultrasound. At the same time, 0.9% normal saline
Control Group (Sufentanil Group):General induction anesthesia was performed and 0.9% normal saline (100ml) was given intravenously
Sponsors
Deyang People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1 Age =65 years, 18.5 < BMI < 28; 2 Asa Grade I, II, III patients undergoing elective abdominal surgery (including radical gastrectomy, radical colon surgery, radical rectum surgery) ; 3 Understanding of the study flow, can operate PCIA (patient-controlled analgesia) equipment, can communicate effectively with researchers; 4 Volunteer and sign informed consent; 5 The operation time was within 4 hours.
Exclusion criteria
Exclusion criteria: 1 A patient who is allergic to the active paracetamol or any of its components; 2 An active bleeding or a high bleeding tendency; 3 Poorly controlled or untreated hypertension (arterial hypertension, resting systolic/diastolic blood pressure over 180/100 mmhg); 4 Untreated or undertreated hyperthyroidism; 5 Those who needed other operations during the same period or had complications that affected the evaluation of the study; 6 Those who were informed and did not want to participate in the study; 7 Post-op intensive-care unit; 8 Patients who have or have had a history of severe mental disorders; 9 Heart failure, previous history of severe angina, history of unstable angina or myocardial infarction in the past six months; 10 Before the study, each patient was tested with visual analogue scale (Vas) , patient-controlled analgesia (PCA) pump operation, answering telephone and understanding of neuropathic pain syndrome scale (NPSI) , patients who did not meet these criteria were excluded from the study; 11 Participants in other clinical trials within the last 3 months; 12 Patients who were on long-term pain medication, or who had used pain medication 7 days before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score;vital signs;Postoperative delirium;Numeric Rating Scale,NRS;Brief Pain Inventory,BPI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Basic information; | — |
Countries
China
Contacts
Public Contactzhi fu zhao
Deyang People's Hospital
Outcome results
None listed