Bilevel positive airway pressure or high-flow nasal oxygenation for gastrointestinal endoscopy with sedation in obesity patients:a multicentre randomised controlled trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400079353

Enrollment

Unknown

Registered

2024-01-01

Start date

2024-01-01

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypoxemia

Interventions

A group:high-flow nasal cannula

B group:BiPAP ventilation

C group:High-flow nasal cannula

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients undergoing elective gastrointestinal endoscopy with sedation 2.Age 18-65 years 3.BMI > 28 kg/m2 4.ASA grade II and III

Exclusion criteria

Exclusion criteria: 1.Emergency endoscopic surgery 2.Patients with severe COPD 3.Patients with hemodynamic instability before surgery 4.Patients at risk of aspiration 5.Pregnant women

Design outcomes

Primary

Measure	Time frame
incidence of SpO2=92%;	—

Secondary

Measure	Time frame
incidence of SpO2=90%;incidence of SpO2=85%;incidence and frequency of anesthesiologist intervention;comsumption of propofol;comsumption of opioids;comsumption of vasoactive drugs;number of operation interruptions;satisfaction score of operator (VAS score);satisfaction score of anesthesiologist (VAS score);	—

Countries

China

Contacts

Public ContactShen Ning

The People's Hospital of Huadu District, Guangzhou

paulshenyh@163.com+86 139 2228 9000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026