painless gastroscopy
Conditions
Interventions
Smoking group:The Dixon sequential method was used, and the initial dose of ciprofol was set to 0.4 mg/kg and the dose gradient was 0.04 mg/kg. Body movement, choking, swallowing and other reactions w
Otherwise, the next patient decreases 0.04 mg/kg. If the Modified Observer's Assessment of Alertness/Sedation Scale(MOAA/S scale) is still> 1 point 3 min after injection of ciprofol, sedation is dire
No smoking group:The Dixon sequential method was used, and the initial dose of ciprofol was set to 0.4 mg/kg and the dose gradient was 0.04 mg/kg. Body movement, choking, swallowing and other reaction
Sponsors
Baoding NO.1 Central Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Male patients to undergo elective painless gastroscopy; 2, age <65 years; 3, BMI <28 kg/m2; 4, ASA grade ? or ?; 5, mouth opening = 2.5 cm; 6, normal head and neck mobility; 7, Mallampati grade ? or ? ; 8, the patient had fully understood the nature of the study, volunteered to participate in the trial and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. History of allergy to test drugs; 2. History of neurological diseases; 3. High risk of inhalation; 4. Expected airway difficulty; 5. Long-term use of sedatives; 7. Acute upper gastrointestinal bleeding; 8. Any condition considered to be unsuitable for any reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| median effective dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects such as bradycardia, hypotension, hypoxia, choking, body movement, and swallowing during the induction period;SpO2, HR and MAP were recorded before anesthesia (T0), 1min after injection (T1) and gastroscopy (T2); | — |
Countries
China
Contacts
Public ContactChunguang Wang
Baoding NO.1 Central Hospital
Outcome results
None listed