Spine metastases
Conditions
Interventions
New treatment strategy and perioperative accelerated recovery group:
Multidisciplinary accelerated recovery interventions based on a new treatment decision-making framework.
Control group:Use standard perioperative measures
Development of a novel decision-making framework for the treatment of spinal metastases:Not applicable
Construction and validation of a perioperative risk prediction model for spinal metastases based on machine learning algorithms:Not applicable
Sponsors
The Fourth Medical Centre of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Age = 18 years; Imaging indicates ESCC 12-point grading as high or very high grade; presence of one or more of the following clinical manifestations: a. Local mechanical or radiating pain with progressive worsening. B. Progressive worsening of sensory dysfunction. C. Impairment of lower limb motor function. D. Impairment of sphincter function; expected survival time > 6 months.
Exclusion criteria
Exclusion criteria: Primary malignant tumors of the spine other than spinal myeloma; intramedullary metastasis of spinal metastatic tumors; the main spinal lesions have already undergone surgery or radiation therapy; combined with severe cardiovascular and cerebrovascular diseases, respiratory system diseases, severe infections, severe hepatic or renal insufficiency, severe coagulation disorders, severe psychological disorders, and other conditions where general anesthesia and surgery are not tolerable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative Blood Loss;Postoperative complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative walking function; The psychological health status of postoperative patients;Quality of life;Postoperative survival outcome; | — |
Countries
China
Contacts
Public ContactYaosheng Liu
The Fourth Medical Centre of Chinese PLA General Hospital
Outcome results
None listed