Effect of auditory stimulation on arousal of comatose patients based on Non-linear Dynamic Analysis of the EEG

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300079310

Enrollment

Unknown

Registered

2023-12-29

Start date

2023-10-18

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorder of Consciousness

Interventions

Disorder of consciousness:NA

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria ? It meets DOC diagnostic criteria and is diagnosed as UWS or MCS; ? Age 18-80 years old; ? Can induce normal brainstem auditory evoked potential; ? No previous history of brain injury; ? The patient's guardian voluntarily participated in the study and signed the informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria ? have hearing impairment; ? The disease continues to worsen, active cerebral hemorrhage or intracranial hypertension has not been controlled; ? Locked-in syndrome, severe cerebral atrophy, hydrocephalus; ? Have a history of epilepsy; ? Severe spasm, resulting in EMG artifacts; ? cranial decompression resection or affect regional EEG amplitude of the skull defect patients.

Design outcomes

Primary

Measure	Time frame
Approximate entropy;Cross-approximate entropy;	—

Countries

China

Contacts

Public ContactZeng Fanshuo

The Second Hospital of Shandong University

zfsdsg1987@126.com+86 182 5313 2710

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 15, 2026