Sarcopenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Meets the diagnostic criteria for "sarcopenia" as outlined in the "2019 Asian Sarcopenia Diagnosis Consensus" published by the Asian Working Group for Sarcopenia; 2) Age between 60 and 80 years old, no gender restrictions; 3) Signs the informed consent form and voluntarily participates in this trial.
Exclusion criteria
Exclusion criteria: 1) Have a background as a professional or semi-professional athlete. 2) Suffer from underlying medical conditions that may lead to malnutrition, such as heart failure, chronic obstructive pulmonary disease (COPD), chronic kidney failure, anorexia, etc. These conditions can result in appetite loss and indigestion among the elderly population. Additionally, mental disorders and cognitive impairment can also contribute to decreased food intake in older individuals. 3) Have underlying diseases that cause muscle wasting, including malignant tumors, neuromuscular disorders, and fractures that have not healed within a three-month period. 4) Experience physical disability or injury to the upper or lower limbs within the past three months which may impact grip strength measurement or walking speed assessment. 5) Take medications known to significantly affect musculoskeletal function. 6) Possess implanted electronic devices or orthopedic metal implants within the body. 7) Struggle with drug or alcohol dependence/abuse issues. 8) Currently enrolled in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient's grip strength change after 8-week treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient's grip strength change rate at week 4 and week 20 ;Skeletal Muscle Index (SMI) change rate;The Short Physical Performance Battery (SPPB);IPAQ (Daily functional evaluation);Subjective Assessment of Treatment Efficacy by Patients;Serum CRP, IL-6, and TNF-a levels;SF-12 (quality of life ); | — |
Countries
China
Contacts
West China Hospital, Sichuan University