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Study on the clinical effect of Li medicine application combined with acupuncture on knee osteoarthritis

Study on the clinical effect of external application of Li medicine combined with acupuncture on knee osteoarthritis

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300079280
Enrollment
Unknown
Registered
2023-12-29
Start date
2024-01-10
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Treatment group:Li medicated application

Sponsors

Dongzhimen Hospital, Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: ? Meet the above diagnostic criteria for KOA; ? 18 years old = age =75 years old; ? Kellgren-Lawrence Grade II or III; ? The mean knee pain NRS=4 in the past 1 week; ? Pain in the past 3 months or more; ? Sign the informed consent to participate in this study voluntarily. Note: Patients who meet the above 6 criteria can be included in this study

Exclusion criteria

Exclusion criteria: ? The painful knee joint to be treated has a history of knee replacement or is in the waiting period for knee surgery; ? Due to rheumatoid arthritis, rheumatoid arthritis, gouty arthritis, psoriatic arthritis, hemophilia Secondary knee osteoarthritis due to arthritis and other causes; ? Other diseases that may affect knee osteoarthritis, such as psoriasis, acute trauma, syphilis, diabetes, etc. ? Pain or dysfunction of lower limbs caused by non-knee joint diseases; ? History or clinical manifestations of skin damage, ulceration, local infection, bleeding tendency (including the current use of anti subjects who are not suitable for acupuncture operation, such as coagulant); ? Received acupuncture treatment within the past 1 month; ? History of severe acute or chronic organic disease or mental illness, blood clotting disorder, past installation of a pacemaker, allergy to metal or history of needle faintness; ? Pregnancy or lactation; ? Observers who have received other relevant treatments that may affect the effect indicators of this study; ? Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency; ? The patient is undergoing treatment with copper or iron. Note: Patients meeting any of the above criteria were excluded

Design outcomes

Primary

MeasureTime frame
WOMAC;

Secondary

MeasureTime frame
NRS;SF- 12;patient efficacy;

Countries

China

Contacts

Public Contactni jinxia

Dongzhimen Hospital, Beijing University of Chinese Medicine

nijinxia118@126.com+86 152 1081 6781

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026