amyotrophic lateral sclerosis
Conditions
Interventions
Amyotrophic Lateral Sclerosis Group:NA
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patient Inclusion Criteria: 1.Patients who possess independent civil conduct capabilities and have given informed consent for this study. 2.Patients who meet the revised El Escorial criteria and are definitively or potentially diagnosed with ALS. 3.Patients initially diagnosed as potentially having ALS, including those confirmed to have ALS during the study period. Healthy Control Inclusion Criteria: 1.Individuals with independent civil conduct capabilities who have given informed consent for this study. 2.Age approximately matching that of the ALS patients included (within 5 years), with the same gender ratio.
Exclusion criteria
Exclusion criteria: Patient Exclusion Criteria: 1.Patients with progressive muscular atrophy and primary lateral sclerosis. 2.Patients in poor general condition or with cardio-pulmonary diseases that prevent them from completing examinations. 3.Patients with other neurological diseases or contraindications for transcranial magnetic stimulation, such as a cardiac pacemaker. Healthy Control Exclusion Criteria: 1.Individuals with other neurological diseases or contraindications for transcranial magnetic stimulation, such as a cardiac pacemaker. 2.Poor general condition or with cardio-pulmonary diseases that prevent them from completing examinations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| short-interval intracortical inhibition(SICI); | — |
Secondary
| Measure | Time frame |
|---|---|
| ALSFR Scale;ECAS Scale; | — |
Countries
China
Contacts
Public ContactXiao Fei
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed