Subjects are surgical patients undergoing general anesthesia with propofol
Conditions
Interventions
Eleveld Group:Targeted infusion using the Eleveld model
Sponsors
Jingzhou Central Hospital
Eligibility
Sex/Gender
All
Age
3 Months to 88 Years
Inclusion criteria
Inclusion criteria: 1) Agreed to participate in this trial and informed consent was signed by the subject or his/her legal representative; 2) Adult and pediatric patients with balanced gender distribution; 3) Patients who were anesthetized with propofol and operated for 1h to 5h; 4) Patients requiring intraoperative arterial cannulation; 5) ASA grade I - III;
Exclusion criteria
Exclusion criteria: 1) Those who have been taking alcohol or antidepressants or anxiolytics for a long time; 2) Those who are allergic to propofol or fat emulsion; 3) Patients undergoing emergency surgery; 4) Pregnant women and those who are breastfeeding; 5) Liver and kidney insufficiency; 6) Those who are less than 3 months old or more than 88 years old; 7) Patients with intraoperative bleeding greater than 400 ml and those with abnormal preoperative temperature; 8) Other conditions deemed unsuitable by the investigators;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cp (plasma drug concentration); | — |
Secondary
| Measure | Time frame |
|---|---|
| Bispectral Index (BIS);Percentage of time that BIS is maintained at the desired value; | — |
Countries
China
Contacts
Public ContactLishen Wang
Jingzhou Central Hospital
Outcome results
None listed