Effect of different doses of lidocaine on cough inhibition in patients undergoing bronchoscopy under general anesthesia

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300079238

Enrollment

Unknown

Registered

2023-12-28

Start date

2024-01-01

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anesthesiology

Interventions

lidocaine 1.0 group:Intravenous lidocaine 1.0mg/kg

lidocaine 1.5 group:Intravenous lidocaine 1.5mg/kg

observation group:5ml 0.9% sodium chloride was given intravenously

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: A total of 135 patients, aged 18-80 years, were examined by bronchoscopy under elective general anesthesia (ASA grade I-III).

Exclusion criteria

Exclusion criteria: (1) BMI =30kg/m2 (2) Reluctance to participate in research (3) Serious heart disease: such as heart dysfunction grade III-IV, unstable heartache, electrocardiogram: AS-S syndrome, pre-excitation syndrome, severe heart block (including sinus, atrioventricular and ventricular block) (4) Liver or mental illness (5) Myasthenia gravis (6) Pregnancy or lactation (7) Allergic to lidocaine, remazolam, remifentanil, and cisatracurium.

Design outcomes

Primary

Measure	Time frame
Minogue scale;VAS pain visual analogue score;Aldrete Score;blood pressure;mean arterial pressure;heart rate;	—

Secondary

Measure	Time frame
oxyhemoglobin saturation;respiratory rate;	—

Countries

China

Contacts

Public Contactkangcuiyao

Shunde Hospital, Southern Medical University, Shunde District, Foshan City, Guangdong Province

234705077@qq.com+86 134 5057 5561

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026