Breast Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who are going to undergo radical mastectomy for breast cancer voluntarily participate in this study and sign an informed consent form 2. ASA ?-? grade 3. Age =18 years old
Exclusion criteria
Exclusion criteria: 1.Severe preoperative hepatic or renal insufficiency. 2. Preoperative underlying diseases, including uncontrolled hypertension, heart disease, diabetes mellitus, chronic obstructive pulmonary disease, etc. 3. Patients with coagulation disorders such as haemophilia. 4. Pre-operative use of immunosuppression or immunodeficiency 5. Preoperative use of anticoagulant drugs 6. Breast cancer patients who need flap transfer or prosthesis implantation. 7. Inability to express themselves, cognitive dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS score at postoperative 24 hours (Resting and Movement);Morphine consumption at postoperative 24 hours;QoR-40 scores at postoperative 1 day;QoR-40 scores at postoperative 3 months; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nerve block puncture success rate;NRS score after extubation;NRS score at postoperative 2 hours;Intraoperaitive opioid consumption;Morphine consumption at postoperative 48 hours;Postoperative 48 hours NRS scores;Postoperative chronic pain scores; | — |
Countries
China
Contacts
Department of Anesthesiology, Chongqing University Cancer Hospital/ Chongqing Cancer Institute/ Chongqing Cancer Center