Brain imaging in patients at high risk of bipolar disorder

Characteristics of brain structure in patients at high risk of bipolar disorder

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300079189

Enrollment

Unknown

Registered

2023-12-27

Start date

2024-01-01

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar disorder

Interventions

Bipolar at risk:no intervention

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: i) patients aged 18 to 35 years, ii) meeting diagnostic criteria for depressive episode (HAMD=17), iii) patients with cyclothymic instability or subthreshold mania, or patients with a family history of BD in a first-degree relative.

Exclusion criteria

Exclusion criteria: i) Diagnosis of bipolar disorder, schizophrenia, or schizoaffective disorder, ii) diagnosis of anxiety disorder, obsessive-compulsive disorder, or substance dependence disorder that explains all psychiatric symptoms, iii) Severe medical illness or medical illness in the acute phase, iv) High risk of suicide.

Design outcomes

Primary

Measure	Time frame
Frontal gray matter volume;	—

Countries

China

Contacts

Public ContactShuzhe Zhou

Peking University Sixth Hospital

zhoushuzhe@bjmu.edu.cn+86 158 1158 8627

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026