hypovolemic shock
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1)Sign informed consent voluntarily (2)Age = 18 years old (3)Hypovolemic shock was diagnosed (meeting one of the following 1+2/3+4/5/6/7) : 1. The patient has a high risk factor or disease (such as trauma, gastrointestinal bleeding, or heat attack) that causes blood volume loss, including fluid loss and blood loss 2. Decreased blood pressure, systolic blood pressure 2s) 6. Spotted skin, pale mucosa or cyanosis, urine volume 100 beats/min or can not be touched, shock index > 1.0.
Exclusion criteria
Exclusion criteria: (1)Have an autoimmune disease (such as cancer, HIV) (2)Patients who received excessive doses of hormone (prednisone 30-100 mg/ d or equivalent dose) and immunosuppressants within 1 month (3)Patients with serious underlying diseases, such as chronic kidney failure and liver failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood product dosage;Vasoactive drug dosage;the time of mean arterial pressure = 65mmHg;difference and dynamic change of arterial lactate, base residual, hematocrit and hemoglobin levels;The time of urine volume, nerve function (disturbance of consciousness) return to normal;The time of mean arterial pressure =65mmHg in 72h; | — |
Countries
China
Contacts
Sun Yat-sen Memorial Hospital, Sun Yat-sen University