Cohort study on rapid eye movement sleep behavior disorder in China
Conditions
Interventions
case series:Nil
Sponsors
Peking University Sixth Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) aged between 40 and 75 years old; 2) iRBD diagnosised by vPSG.
Exclusion criteria
Exclusion criteria: 1. History of other disorders causing RBD, such as neurodegenerative diseases, encephalitis, narcolepsy, etc; 2. History of other neurological disorders (such as stroke, demyelinating diseases, traumatic brain injury, etc) ; 3. History of psychiatric disorders, such as major depression, bipolar disorder, schizophrenia (according to DSM-5 diagnostic criteria) ; 4. History of alcohol or substance abuse/addiction within the past two years (according to DSM-5 diagnostic criteria) ; 5. Participants currently experiencing acute or unstable mental or physical conditions that would significantly impede their participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of olfactory function;Movement Disorders Society Unified Parkinson's Disease rating scale, MDS-UPDRS score;Cognitive function assessment;orthostatic hypotension;signal value of functional connectivity;functional connectivity network;oculomotor function;ability of gait controlling;uptake of dopamine transporter in basal ganglia; | — |
Countries
China
Contacts
Public ContactYuan Junliang
Peking University Sixth Hospital
Outcome results
None listed