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A clinical study on the combined use of Remimazolam and Ciprofol in inhibiting cough reflex during bronchoscopy in elderly patients

A clinical study on the combined use of Remimazolam and Ciprofol in inhibiting cough reflex during bronchoscopy in elderly patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300079139
Enrollment
Unknown
Registered
2023-12-26
Start date
2023-12-26
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough reflex

Interventions

CIP:Ciprofol
RMZ-CIP:Remimazolam, Ciprofol

Sponsors

First Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 60-90 years old 2. ASA I-III grade 3. plan to undergo bronchoscopy under total intravenous anesthesia

Exclusion criteria

Exclusion criteria: 1 Patients with contraindications for bronchoscopy examination; 2 Patients with difficult airways; 3 Patients with severe airway stenosis and acute infection; 4 Patients with study drugs allergy; 5 Patients with severe hypertension (systolic blood pressure = 180mmHg, or diastolic blood pressure = 110mmHg); 6 Patients with severe arrhythmia; 7 Patients classified as New York Heart Association (NYHA) Class III or above with severe heart failure; 8 Patients with liver or kidney dysfunction; 9 Women in childbirth, childbirth, or lactation; 10 Patients whose preoperative consciousness state is difficult to independently or accurately determine; 11 Patients with a history of using psychotropic drugs.

Design outcomes

Primary

MeasureTime frame
Incidene of cough reflex;

Secondary

MeasureTime frame
Vital sign;Characters of surgery and anesthesia;Preoperative and postoperative blood gas analysis;Check completion rate;The patient's comfort evaluation, the satisfaction score of the operator;

Countries

China

Contacts

Public ContactXuehai Guan

First Affiliated Hospital of Guangxi Medical University

guan_xh@aliyun.com+86 771 535 6250

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026